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Everything You Need to know about Glutathione: Sources and Benefits

Published : July 2, 2021 4 mins read Updated On : May 30, 2024

Glutathione is a simple molecule and is known as a super antioxidant, which aids in anti-ageing and promotes skin health. It comprises of three crucial amino acids cysteine, glutamic acid and glycine. It is manufactured by the body’s own liver cells. Liver being the main organ for detoxification. It neutralizes free radicals formed in our body, boosts immunity. It exists in two forms in our body i.e. reduced and oxidized form.

Food Sources of Glutathione
• Spinach
• Avocados
• Asparagus
• Okra
• Tomatoes
• Oranges
• Grapefruit
• Strawberries
• Chicken
• Fish

Benefits of Glutathione for Skin

• Helps to provides antioxidant effects
Glutathione is a powerful antioxidant. Glutathione helps in neutralising the free radicals formulated due to intense exposure to ultraviolet radiation and environmental pollutants. Free radicals are responsible for causing significant damage to skin cells and cause premature skin ageing leading to wrinkles, fine lines, and dark spots.

• Helps to reduce oxidative stress
Oxidative stress happens from an imbalance between free radical production and the body's antioxidant defenses. High oxidative stress levels may be the cause of various diseases such as diabetes, cancer, and rheumatoid arthritis. Glutathione aids in mitigating the effects of oxidative stress, potentially lowering the risk of disease.

• Helps in skin lightning
Glutathione inhibits melanin synthesis by suppressing the activity of tyrosinase, the enzyme responsible for melanin production. Additionally, glutathione acts as an antioxidant, reducing oxidative stress in the skin, which can contribute to hyperpigmentation. Furthermore, glutathione may help to repair damaged skin cells and inhibit the transfer of melanin to the skin's surface, resulting in a brighter complexion over time.

• Helps in skin elasticity
Glutathione can boost the body's collagen and elastin levels, aiding in the restoration of lost skin elasticity and cellular repair. Additionally, it supports the retention of hyaluronic acid, thus promoting skin hydration.
These elements collectively contribute to enhancing the appearance of fine lines, wrinkles, and achieving smoother, more youthful-looking skin. The combination of vitamin C and glutathione not only repairs the skin but also promotes its whitening effects.

• Helps to detoxify the body
Glutathione acts as an agent for the removal of excess toxins in our body aiding in the detoxification process. Detoxification is vital as removal of noxious substances helps in keeping our skin healthy and full of life.

Symptoms of Glutathione Deficiency

• Lack of glow and healthy skin
• Uneven skin tone
• Premature ageing
• Hair fall
• Loose skin

Why Do You Need Glutathione Supplements?
One of the chief reasons you need glutathione supplements is STRESS? Due to the ranging lifestyle conditions and poor nutrition our body can't afford to retain its energy, hence the need for supplements. Other factors include:
• Environmental factors (Pollution)
• Premature ageing
• Lack of sleep
• Radiations
• Trauma

How to Incorporate Glutathione in Your Skincare Routine?
• Consult a Dermatologist: Before starting any new skincare regimen, it's crucial to consult a dermatologist, especially when introducing potent ingredients like glutathione.
• Choose the Right Formulation: Glutathione comes in various forms such as oral supplements, topical creams, serums, and injections. Determine which form suits your preferences and skincare needs best.
• Topical Application: Opt for serums or creams containing glutathione for direct application to the skin. Apply a small amount to clean, dry skin, focusing on areas of concern such as hyperpigmentation or uneven skin tone.
• Combine with Other Ingredients: Glutathione works synergistically with other skincare ingredients like vitamin C, vitamin E, and alpha hydroxy acids (AHAs). Look for products that combine glutathione with these ingredients for enhanced benefits.
• Consistency is Key: Incorporate glutathione into your daily skincare routine for optimal results. Consistent use over time is essential for noticing improvements in skin tone and texture.
• Protect Your Skin: Glutathione can make your skin more sensitive to sunlight. Therefore, always apply a broad-spectrum sunscreen with SPF 30 or higher during the day to protect your skin from UV damage.
• Monitor for Sensitivity: Keep an eye out for any signs of irritation or allergic reactions when using glutathione. If you experience any adverse effects, discontinue use and consult a dermatologist.


While many recognise glutathione solely for its skin brightening properties, its role extends beyond depigmentation to encompass comprehensive skin rejuvenation and restoration.
Its advantages include imparting a radiant complexion, managing acne and diminishing acne scars, addressing skin concerns arising from sun exposure and environmental damage, as well as enhancing pigmentation, tan, and freckles while combating wrinkles.
Incorporating glutathione into your skincare regimen at any stage can yield optimal benefits for your skin health and appearance.


1. What does glutathione do for the body?
Glutathione serves as a powerful antioxidant, aiding in detoxification, supporting immune function, regulating cell growth, and promoting overall cellular health and protection against oxidative damage.

2. What food is the highest in glutathione?
Foods highest in glutathione include fruits like avocado, watermelon, and oranges, vegetables like spinach, asparagus, and broccoli, and lean proteins like fish and poultry.

3. Is it good to take glutathione every day?
It's generally safe to take glutathione supplements daily, but it's essential to consult with a healthcare professional to determine the appropriate dosage and ensure it aligns with individual health needs.

4. What are the side effects of glutathione?
Common side effects of glutathione supplements may include nausea, stomach upset, and allergic reactions.

Soumil Vartak
Health and Fitness enthusiast

Soumil is really passionate about health and fitness. He provides great insight on various trends about health and fitness. By writing about these topics he try to provide key insight on diet and e... Read More


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